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UpToDate
https://www.uptodate.com/contents/search?search=apixaban
Dose reduction of apixaban to 2.5 mg twice daily may be necessary in patients with … Risks and prevention of bleeding with oral anticoagulants …aspirin plus apixaban arm (1.3 versus 0.5 percent; HR 2.59, 95% CI 1.50-4.46).
DA: 61 PA: 32 MOZ Rank: 63
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Patient education: Ischemic stroke treatment (Beyond the Basics) - UpToDate
https://www.uptodate.com/contents/ischemic-stroke-treatment-beyond-the-basics
Aug 23, 2021 · Low-dose anticoagulant therapy with heparin or low molecular weight heparin is sometimes used for people with ischemic stroke who cannot move due to paralysis from the stroke. This treatment can help to prevent blood clots from forming in the leg veins or other veins in the body, which can cause pain and swelling.
DA: 41 PA: 25 MOZ Rank: 9
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Switching between oral anticoagulants - UpToDate
https://www.uptodate.com/contents/image?imageKey=HEME/120639
Overlap warfarin with apixaban until the INR is therapeutic on warfarin, testing right before the next apixaban dose to minimize the effect of apixaban on INR elevation (ASH).* Edoxaban: Reduce dose by half (eg, from 60 to 30 mg daily or from 30 to 15 mg daily) and begin warfarin concurrently (PI).
DA: 9 PA: 76 MOZ Rank: 79
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Patient education: Deep vein thrombosis (DVT) (Beyond the ... - UpToDate
https://www.uptodate.com/contents/deep-vein-thrombosis-dvt-beyond-the-basics
Mar 17, 2022 · An advantage of initiating treatment with a DOAC is that some DOACs (apixaban, rivaroxaban) can be started right after a clot is diagnosed without the need for an initial 5 to 10 days of an injectable blood thinner (eg, LMW heparin). ... to get regular blood tests to monitor the blood thinning effect of warfarin and ensure that you are taking ...
DA: 86 PA: 37 MOZ Rank: 8
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Atrial fibrillation in adults: Use of oral anticoagulants - UpToDate
https://www.uptodate.com/contents/atrial-fibrillation-in-adults-use-of-oral-anticoagulants
May 16, 2022 · Apixaban – The dose of apixaban is 5 mg twice daily (approximately 12 hours apart) unless the patient has two or more of the following: age ≥80 years, body weight ≤60 kg, or serum creatinine level ≥1.5 mg/dL [133 micromol/L]). Then the dose of apixaban is 2.5 mg twice daily. This dose adjustment is for moderate renal impairment.
DA: 9 PA: 100 MOZ Rank: 9
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UpToDate
https://www.uptodate.com/contents/heparin-and-lmw-heparin-dosing-and-adverse-effects
Jun 08, 2022 · Learn how UpToDate can help you. Select the option that best describes you. ... Julian JA, et al. Comparison of fixed-dose weight-adjusted unfractionated heparin and low-molecular-weight heparin for acute treatment of venous thromboembolism. ... Gulseth MP. Transitioning hospitalized patients from rivaroxaban or apixaban to a continuous ...
DA: 51 PA: 90 MOZ Rank: 9
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Perioperative management of patients receiving anticoagulants - UpToDate
https://www.uptodate.com/contents/perioperative-management-of-patients-receiving-anticoagulants/print
Mar 11, 2022 · Refer to UpToDate topics on treatment of bleeding in patients receiving a DOAC or perioperative management of patients receiving a DOAC for additional information on administration, risks, and alternative therapies. ... • Omit apixaban for one day before the procedure (last dose of apixaban on day minus 2).
DA: 6 PA: 79 MOZ Rank: 27
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Drug interaction resources: mind the gaps - Australian Prescriber
https://www.nps.org.au/australian-prescriber/articles/drug-interaction-resources-mind-the-gaps
Feb 03, 2020 · The mechanisms of drug–drug interactions vary. 2,3 Clinicians need to understand the drug’s pharmacology including metabolic pathways to determine both pharmacodynamic (altered effect) and pharmacokinetic (altered concentration) interactions. It can be particularly complex to assess the clinical significance of interactions from multiple drugs which each have …
DA: 94 PA: 34 MOZ Rank: 51
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UpToDate
https://www.uptodate.com/contents/search?search=eliquis
Dose reduction of apixaban to 2.5 mg twice daily may be necessary in patients with … Risks and prevention of bleeding with oral anticoagulants …aspirin plus apixaban arm (1.3 versus 0.5 percent; HR 2.59, 95% CI 1.50-4.46).
DA: 37 PA: 44 MOZ Rank: 25
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UpToDate
https://www.uptodate.com/contents/image?imageKey=HEME/120639
Overlap warfarin with apixaban until the INR is therapeutic on warfarin, testing right before the next apixaban dose to minimize the effect of apixaban on INR elevation (ASH).* Edoxaban: Reduce dose by half (eg, from 60 to 30 mg daily or from 30 to 15 mg daily) and begin warfarin concurrently (PI).
DA: 60 PA: 35 MOZ Rank: 71
