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Sodium Nitrite Toxicity - WebMD
https://www.webmd.com/first-aid/sodium-nitrite-toxicity
WebReference. Sodium Nitrite Toxicity. Medically Reviewed by Sabrina Felson, MD on July 15, 2023. Written by Alexandra Benisek. What Is Sodium Nitrite Used For? What Causes Sodium Nitrite...
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Fatal Sodium Nitrite Poisoning: Key Considerations for ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/33074043/
WebEMS professionals should consider sodium nitrite toxicity in patients with a suspected overdose who present with a cyanotic appearance, pulse oximetry that remains around 85% despite oxygen, and dark brown blood seen on venipuncture.
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Survival after self‐poisoning with sodium nitrite: A case report
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931305/
WebMar 17, 2022 · Sodium nitrite toxicity is capable of causing severe methemoglobinemia with high mortality. Prompt identification is crucial. We discuss the important implications in regard to media coverage, imitative suicide, and accessibility of sodium nitrite.
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Sodium nitrite - Wikipedia
https://en.wikipedia.org/wiki/Sodium_nitrite
WebToxicity. Sodium nitrite is toxic. The LD 50 in rats is 180 mg/kg and in humans LD Lo is 71 mg/kg. The mechanism by which sodium nitrite causes death is methemoglobinemia. The oftentimes severe methemoglobinemia found in sodium nitrite poisoning cases results in systemic hypoxia, metabolic acidosis, and cyanosis.
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Sodium Nitrite Intoxication and Death: Summarizing Evidence to
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9654862/
WebOct 27, 2022 · Sodium nitrite causes increased methemoglobin, resulting in systemic hypoxia, metabolic acidosis, and cyanosis. Since sodium nitrite is a preservative, the ingestion of foods containing an excessive amount of this substance can also cause acute intoxication up to death.
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Suicide attempt using sodium nitrite ordered on the... : Medicine
https://journals.lww.com/md-journal/Fulltext/2022/07150/Suicide_attempt_using_sodium_nitrite_ordered_on.28.aspx
WebJul 15, 2022 · The primary toxicity mechanism of sodium nitrite is the oxidation of ferrous iron (Fe2+) of hemoglobin to methemoglobin (MetHb) containing ferric iron (Fe3+) with consequent methemoglobinemia, in which it loses its ability to bind and transport oxygen.
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Rising incidence and high mortality in intentional sodium nitrite
https://pubmed.ncbi.nlm.nih.gov/33787434/
WebSodium Nitrite. The incidence of intentional self-poisoning with sodium nitrite has been increasing since 2017. Many of these exposures result in toxicity requiring antidotal therapy, and a high mortality rate was observed. Recent literature indicates that this trend may be the result of ready access to this poison ….
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Survival after self-poisoning with sodium nitrite: A case report
https://onlinelibrary.wiley.com/doi/full/10.1002/emp2.12702
WebMar 17, 2022 · Sodium nitrite toxicity is capable of causing severe methemoglobinemia with high mortality. Prompt identification is crucial. We discuss the important implications in regard to media coverage, imitative suicide, and accessibility of sodium nitrite. 1 INTRODUCTION.
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Increasing use of sodium nitrite in suicides—an emerging trend
https://link.springer.com/article/10.1007/s12024-022-00471-8
WebMar 25, 2022 · Abstract. Sodium nitrite (NaNO 2) is a compound with broad practical applications in food preservation, automotive maintenance, and animal control. Sodium nitrite is also potentially fatal when ingested, as it interferes with the ability of red blood cells to transport oxygen.
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Sodium nitrite poisoning: A series of 20 fatalities in which post
https://pubmed.ncbi.nlm.nih.gov/36848754/
WebPMID: 36848754. DOI: 10.1016/j.forsciint.2023.111610. Abstract. Sodium nitrite has several industrial applications however its accidental or intentional ingestion has been associated with severe toxicity and death.
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