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Rucaparib - Wikipedia
https://en.wikipedia.org/wiki/Rucaparib
Web ResultRucaparib, sold under the brand name Rubraca, is a PARP inhibitor used as an anti-cancer agent. Rucaparib is a first-in-class pharmaceutical drug targeting the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1). It is taken by mouth.
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Rucaparib | FDA - U.S. Food and Drug Administration
https://www.fda.gov/drugs/resources-information-approved-drugs/rucaparib
Web ResultOn December 19, 2016, the U.S. Food and Drug Administration granted accelerated approval to rucaparib (RUBRACA, Clovis Oncology Inc.) for treatment of patients with deleterious BRCA mutation...
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Rucaparib or Physician’s Choice in Metastatic Prostate Cancer
https://www.nejm.org/doi/full/10.1056/NEJMoa2214676
Web ResultFeb 16, 2023 · In a phase 2 study, rucaparib, an inhibitor of poly (ADP-ribose) polymerase (PARP), showed a high level of activity in patients who had metastatic, castration-resistant prostate cancer associated...
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Rucaparib Uses, Side Effects & Warnings - Drugs.com
https://www.drugs.com/mtm/rucaparib.html
Web ResultJan 13, 2023 · Rucaparib is used to treat ovarian cancer, fallopian tube cancer, or primary peritoneal cancer (cancer of the membrane lining the organs inside your abdomen). Rucaparib is sometimes used for these conditions only if your cancer has a specific genetic marker (an abnormal "BRCA" gene). Your doctor will test you …
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Rucaparib: Uses, Interactions, Mechanism of Action | DrugBank …
https://go.drugbank.com/drugs/DB12332
Web ResultRucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair. 1 Rucaparib is proposed to work in several PARP-dependent and PARP-independent mechanisms of action; however, it causes a unique effect of synthetic lethality.
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Rucaparib (Rubraca) | Cancer information | Cancer Research UK
https://www.cancerresearchuk.org/about-cancer/treatment/drugs/rucaparib
Web ResultSep 11, 2023 · Rucaparib is a targeted cancer drug . It is also known as Rubraca. It is a treatment for a number of different cancer types. You pronounce rucaparib as roo-ka-pur-ib. You may have rucaparib after treatment with platinum chemotherapy if it has worked. This is called maintenance treatment.
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Rucaparib (Oral Route) Description and Brand Names - Mayo Clinic
https://www.mayoclinic.org/drugs-supplements/rucaparib-oral-route/description/drg-20406019
Web ResultFeb 1, 2024 · Descriptions. Rucaparib is used as maintenance treatment in patients with ovarian cancer, fallopian tube cancer, or primary peritoneal cancer that has come back. It is only used in patients who have a certain type of inherited (germline) or acquired (somatic) abnormal BRCA gene.
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Rucaparib: MedlinePlus Drug Information
https://medlineplus.gov/druginfo/meds/a617002.html
Web ResultRucaparib is in a class of medications called poly (ADP-ribose) polymerase (PARP) inhibitors. It works by killing cancer cells. How should this medicine be used? Rucaparib comes as a tablet to take by mouth. It is usually taken with or without food twice daily, about 12 hours apart. Take rucaparib at around the same times every …
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Rubraca | European Medicines Agency
https://www.ema.europa.eu/en/medicines/human/EPAR/rubraca
Web ResultOct 10, 2018 · rucaparib. Medicine Human. Overview. Rubraca is a cancer medicine for treating high-grade cancers of the ovary, fallopian tubes (the tubes connecting the ovaries to the uterus) and the peritoneum (the membrane lining the abdomen).
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Rucaparib Camsylate - NCI - National Cancer Institute
https://www.cancer.gov/about-cancer/treatment/drugs/rucaparibcamsylate
Web ResultYes. FDA label information for this drug is available at DailyMed. Use in Cancer. Rucaparib camsylate is approved to treat: Ovarian epithelial, fallopian tube, or primary peritoneal cancer. It is used as maintenance therapy in adults with recurrent cancer who are having a complete or partial response to platinum chemotherapy.
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