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Phenotypic screening: the future of antibody discovery - PubMed
https://pubmed.ncbi.nlm.nih.gov/26440132/
WEBHere, we review successful phenotypic screens, including those used to isolate antibodies against cancer and infectious agents. We also consider exciting advances in the expression and phenotypic screening of antibody repertoires in single cell autocrine systems. Author: Andrea L. Gonzalez-Munoz, Ralph R. Minter, Steven J. Rust Publish Year: 2016
Author: Andrea L. Gonzalez-Munoz, Ralph R. Minter, Steven J. Rust
Publish Year: 2016
DA: 4 PA: 17 MOZ Rank: 68
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Phenotypic screening: the future of antibody discovery
https://www.sciencedirect.com/science/article/pii/S1359644615003700
WEBJan 1, 2016 · If antibody phenotypic screens are to lead to greater success in the clinic, the initial screen needs to reflect the disease state as closely as possible [27]. Many … Author: Andrea L. Gonzalez-Munoz, Ralph R. Minter, Steven J. Rust Publish Year: 2016
Author: Andrea L. Gonzalez-Munoz, Ralph R. Minter, Steven J. Rust
Publish Year: 2016
DA: 83 PA: 71 MOZ Rank: 45
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Phenotypic drug discovery: recent successes, lessons learned
https://www.nature.com/articles/s41573-022-00472-w
WEBMay 30, 2022 · In our experience, phenotypic screening using a chemical library containing highly selective legacy compounds from TDD programmes can provide hits …
DA: 22 PA: 71 MOZ Rank: 95
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A cell-based phenotypic library selection and screening ... - Nature
https://www.nature.com/articles/s41598-022-05058-5
WEBJan 21, 2022 · Article. Open access. Published: 21 January 2022. A cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional …
DA: 47 PA: 48 MOZ Rank: 89
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Phenotypic Screening the Future of Antibody Discovery
http://csmres.co.uk/cs.public.upd/article-downloads/Phenotypic-screening-the-future-of-antibody-discovery.pdf
WEBto assume that phenotypic screening, which is target agnostic and identifies molecules based on functionality in cell-based systems before target elucidation, provides a means …
DA: 1 PA: 3 MOZ Rank: 60
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Phenotypic screening: the future of antibody discovery.
https://europepmc.org/article/MED/26440132
WEBOct 9, 2015 · Most antibody therapeutics have been isolated from high throughput target-based screening. However, as the number of validated targets diminishes and the target …
DA: 65 PA: 60 MOZ Rank: 52
