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Development of mRNA Vaccines: Scientific and Regulatory Issues
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910833/
Jan 23, 2021 · 2. Development of mRNA Vaccines. The demonstration of the use of mRNA as a potential in-vivo gene-delivery technology was published in 1990, when the direct injection of “naked” … Author: Ivana Knezevic, Margaret A. Liu, Keith Peden, Tiequn Zhou, Hye Na Kang Publish Year: 2021
Author: Ivana Knezevic, Margaret A. Liu, Keith Peden, Tiequn Zhou, Hye Na Kang
Publish Year: 2021
DA: 62 PA: 49 MOZ Rank: 4
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The Long History of mRNA Vaccines | Johns Hopkins | Bloomberg …
https://publichealth.jhu.edu/2021/the-long-history-of-mrna-vaccines
Oct 06, 2021 · Already, vaccine manufacturers are developing mRNA vaccines to protect against other respiratory viruses such as the flu. Moderna is exploring applications of the technology to protect …
DA: 50 PA: 9 MOZ Rank: 86
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Developing mRNA-vaccine technologies - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597572/
Nov 01, 2012 · Despite the sensitivity of the molecule to the virtually omnipresent ribonucleases (RNases), 1 mRNA as a therapeutic was first promoted in 1989 after the development of a broadly … Author: Thomas Schlake, Andreas Thess, Mariola Fotin-Mleczek, Karl Josef Kallen Publish Year: 2012
Author: Thomas Schlake, Andreas Thess, Mariola Fotin-Mleczek, Karl Josef Kallen
Publish Year: 2012
DA: 45 PA: 54 MOZ Rank: 14
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Understanding mRNA COVID-19 Vaccines | CDC
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mrna.html
Jun 16, 2022 · Researchers have been studying and working with mRNA vaccines for decades. Interest has grown in these vaccines because they can be developed in a laboratory using readily available …
DA: 1 PA: 13 MOZ Rank: 23
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Development and Delivery Systems of mRNA Vaccines - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354200/
Jul 27, 2021 · mRNA vaccines are third-generation nucleic acid vaccines developed on the basis of the first-generation attenuated/inactivated vaccines and the second-generation subunit vaccines. At …
DA: 5 PA: 99 MOZ Rank: 91
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mRNA Technology & COVID-19 Vaccine Development | Penn …
https://www.pennmedicine.org/mrna
Two Penn researchers, Katalin Karikó, PhD, and Drew Weissman, MD, PhD, invented messenger RNA (mRNA) technology that serves as the foundation of the Pfizer/BioNTech and Moderna vaccines. Drs. …
DA: 88 PA: 70 MOZ Rank: 68
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Advances in COVID-19 mRNA vaccine development - PubMed
https://pubmed.ncbi.nlm.nih.gov/35322018/
Various techniques have been employed in the development of COVID-19 vaccines. Among these, the COVID-19 messenger RNA (mRNA) vaccine has been drawing increasing attention owing to its great …
DA: 91 PA: 48 MOZ Rank: 63
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The Development of mRNA Vaccines for Infectious Diseases: …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668227/
Dec 09, 2021 · one of the nucleic acid vaccine approaches involves the development of messenger ribonucleic acid (mrna) vaccines. 8 the first mrna vaccine was developed in rats to reverse …
DA: 38 PA: 56 MOZ Rank: 1
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The mRNA vaccine development landscape for infectious diseases
https://www.nature.com/articles/d41573-022-00035-z
Feb 11, 2022 · Two major technical considerations for mRNA vaccine development are the mRNA construct format that encodes the immunogen and the delivery vehicle that facilitates cellular entry …
DA: 31 PA: 87 MOZ Rank: 48
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An Update on Self-Amplifying mRNA Vaccine Development
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911542/
Jan 28, 2021 · The use of mRNA vaccines for pandemic response has been well described previously in preclinical [12,21,22,23,24,25,26,27,28,29,30,31,32,33] and clinical settings , but this is the first time …
DA: 60 PA: 85 MOZ Rank: 81
