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Cell Products | ATCC
https://www.atcc.org/cell-products
Web ResultATCC has the world’s largest and most extensive product catalog of human and animal cell lines for research purposes. The cell biology collection includes more than 4,000 continuous cell lines available by species, tissue/disease types, and signaling pathways.
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Frontiers | MC38 colorectal tumor cell lines from two different …
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1102282/full
Web ResultFeb 23, 2023 · MC38-L cells were cultured in IMDM (ATCC, 30-2005) containing 8% Fetal Bovine Serum (FBS), 2 mM L-glutamine and 50 µM beta-mercaptoethanol. MC38-K cells were cultured in DMEM (ATCC, 30-2002) supplemented with 10% FBS, 10 mM HEPES and 1X nonessential amino acids (NEAA).
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MC-38 Cell Line - Kerafast
https://www.kerafast.com/productgroup/665/mc-38-cell-line
Web ResultMC-38 Cell Line derived from C57BL6 murine colon adenocarcinoma cells. From the laboratories of James W. Hodge, PhD, MBA and Jeffrey Schlom, PhD, National Cancer Institute/NIH. This product is for sale to Nonprofit customers only.
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Targeting immune checkpoints potentiates immunoediting and
https://www.nature.com/articles/s41467-017-02424-0
Web ResultJan 2, 2018 · Analyses of wild-type and immunodeficient RAG1 knockout mice transplanted with MC38 cells reveal that upregulation of checkpoint molecules and infiltration by Tregs are the major tumor escape...
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Different syngeneic tumors show distinctive intrinsic tumor ... - Nature
https://www.nature.com/articles/s41598-022-07153-z
Web ResultFeb 28, 2022 · We modeled loss of function (LOF) in four common anti-PD-1 antibody-responsive syngeneic tumors, MC38, Hepa1-6, CT-26 and EMT-6, by systematical depleting a series of TIL lineages to explore the...
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MC38 colorectal tumor cell lines from two different sources display
https://pubmed.ncbi.nlm.nih.gov/36969213/
Web ResultMar 8, 2023 · Introduction: The cell line MC38 is a commonly used murine model for colorectal carcinoma. It has a high mutational burden, is sensitive to immune checkpoint immunotherapy and endogenous CD8+ T cell responses against neoantigens have been reported. Methods: Here, we re-sequenced exomes and …
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Targeting immune checkpoints potentiates immunoediting and …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750210/
Web ResultJan 2, 2018 · Analyses of wild-type and immunodeficient RAG1 knockout mice transplanted with MC38 cells reveal that upregulation of checkpoint molecules and infiltration by Tregs are the major tumor escape mechanisms. Our results show that the effects of immunoediting are weak and that neutral accumulation of mutations …
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A syngeneic MC38 orthotopic mouse model of colorectal cancer …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9550231/
Web ResultSep 28, 2022 · MC38 and CT26 cells are commonly used murine colorectal cancer cell lines with clinically relevant mutations. While CT26 cells have been orthotopically implanted with high fidelity, successful engraftment of orthotopic MC38 tumors varies greatly between studies.
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Bispecific antibody simultaneously targeting PD1 and HER2
https://www.nature.com/articles/s41401-021-00683-8
Web ResultMay 14, 2021 · MC38 syngeneic tumor models were established in 18–20 g female PD-1 humanized mice (B6-Pdcd1 em1(hPdcd1)Vst /Vst, Vital star Biotech) by subcutaneous injection of 1 × 10 6 MC38 cells.
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Cellosaurus cell line MC-38 (CVCL_B288)
https://www.cellosaurus.org/CVCL_B288
Web ResultCell line name. MC-38. Synonyms. MCA-38; MCA 38; MCA38; MC38; Mouse Colon 38; Murine Carcinoma-38; Colon 38; Colon-38; Colon38; C38. Accession. CVCL_B288. Resource Identification Initiative. To cite this cell …
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