Keyword Analysis & Research: k562 cell line

wikipedia.org

https://en.wikipedia.org/wiki/K562_cells

K562 cells were the first human immortalised myelogenous leukemia cell line to be established. K562 cells are of the erythroleukemia type, and the cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis. The cells are non-adherent and rounded, are positive

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atcc.org

https://www.atcc.org/products/ccl-243

K-562 cells are lymphoblasts isolated from the bone marrow of a 53-year-old chronic myelogenous leukemia patient. The K-562 cell line is widely used as a highly sensitive in vitro target for the natural killer assay. Product category Human cells Organism Homo sapiens, human Morphology lymphoblast Tissue Bone; Marrow Disease

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creative-biogene.com

https://www.creative-biogene.com/support/k562-cell-line.html

K562 cells were established the first human immortalized myelogenous leukemia line. This cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis. They can be used as a highly sensitive target for the in vitro natural killer assay. Disease: Chronic myelogenous leukemia (CML) Organism: Homo sapiens, human Morphology: Lymphoblast Tissue: Bone marrow

Disease: Chronic myelogenous leukemia (CML)

Organism: Homo sapiens, human

Morphology: Lymphoblast

Tissue: Bone marrow

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sciencedirect.com

https://www.sciencedirect.com/topics/medicine-and-dentistry/k562-cells

K-562 cells lack human leukocyte antigen (HLA) class-I and -II expression, and, consequently, are a gold-standard cell line for evaluating NK cell effector activity. 2. K-562 cells grow as a suspension and can be maintained in 25 cm 2 or 75 cm 2 flasks, as well as in 60 mm- or 100 mm-diameter Petri dishes for cell culture depending on the laboratory requirements.

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nih.gov

https://pubmed.ncbi.nlm.nih.gov/367973/

We have studied the surface membrane properties of the human leukemic cell line K562 which previously has been reported to represent an early stage of granulocyte maturation. The surface glycoprotein pattern of the K562 cells obtained after galactose oxidase-NaB [3H]4 labelling and slab gel electrophoresis shows striking similarities with that of normal erythrocytes but is … Author: Leif C. Andersson, Kenneth Nilsson, Carl G. Gahmberg Publish Year: 1979

Author: Leif C. Andersson, Kenneth Nilsson, Carl G. Gahmberg

Publish Year: 1979

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nih.gov

https://pubmed.ncbi.nlm.nih.gov/789258/

Oct 15, 1976 · The K562 cell line derived from a CML patient in blast crisis was examined for properties of B and T lymphocytes and cell lines. K562 lacks the B markers of immunoglobulins, Epstein-Barr virus (EBV) genome and associated nuclear antigen, and receptors for EBV. A low proportion of cells from rosettes with sheep erythrocytes, the …

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sciencedirect.com

https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/k562-cells

In human NK cell assays, the leukemic K562 cells are commonly used as targets for their high and reproducible sensitivity to NK lysis. The K562 cell line was originally considered as a highly undifferenciated cell line of the granulocytic lineage (Lozzio and Lozzio, 1975 ).

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expasy.org

https://web.expasy.org/cellosaurus/CVCL_0004

Apr 04, 2012 · The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript. Mol. Cell. Biol. 6:607-616(1986) PubMed= 2446768 ; DOI= 10.1007/BF02797342

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nih.gov

https://pubmed.ncbi.nlm.nih.gov/9116119/

The human erythroleukaemic cell line K562, in response to various chemical agents, undergoes differentiation and exhibits exclusive production of fetal and embryonic haemoglobins. In this study we have compared the efficiency of natural growth factors interleukin-3 and erythropoietin and three chemical inducers such as dimethyl sulfoxide (DMSO, 1.9%), phorbol-12-myristate …

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nih.gov

https://pubmed.ncbi.nlm.nih.gov/27177665/

stimulation with nk-sensitive k562 cells is known to augment nk cell proliferation to il-2, il-15, and il-21 in combination.recently, remarkable nk cell-expansion rates are achieved when genetically engineered (ge) feeder cells are used. dr. dario campana's group found that membrane-bound il-15 and 4-1bbl, coexpressed by k562 cells, acted …

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