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Huh-7 Origin - HUH-7 Cell Line
https://huh7.com/
webHuh-7 is an immortal cell line composed of epithelial-like, tumorigenic cells. The majority of Huh-7 cells show a chromosome number between 55 and 63 (mode 60) and are highly heterogeneous. These cells are adherent to the surface of flasks or plates and typically grow as 2D monolayers.
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Identification of Characteristic Genomic Markers in Human …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7581915/
webOct 9, 2020 · Abstract. The human hepatoma-derived HuH-7 cell line and its derivatives (Huh7.5 and Huh7.5.1) have been widely used as a convenient experimental substitute for primary hepatocytes. In particular, these cell lines represent host cells suitable for propagating the hepatitis C virus (HCV) in vitro.
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A novel differentiated HuH-7 cell model to examine bile acid
https://www.nature.com/articles/s41598-022-18174-z
webAug 22, 2022 · HuH-7 cells cultured with DEX, DEX + DMSO and overlay showed increased [3 H]-TCA accumulation in “Cells + Bile” and in “Cells” compared to control cells with and without overlay.
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Cellosaurus cell line Huh-7 (CVCL_0336)
https://www.cellosaurus.org/CVCL_0336
webApr 4, 2012 · Synonyms. HuH-7; HUH-7; HuH7; Huh7; HUH7; HUH7.0; JTC-39; Japanese Tissue Culture-39. Accession. CVCL_0336. Resource Identification Initiative. To cite this cell line use: Huh-7 (RRID:CVCL_0336) Comments. Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines …
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Huh7 - Wikipedia
https://en.wikipedia.org/wiki/Huh7
webHuh7 is an immortalised cell line and may be grown in the laboratory for research purposes. According to the web site huh7.com, it is "a well differentiated hepatocyte -derived carcinoma cell line, originally taken from a liver tumor in a …
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Establishment and Characterization of a New Cell Line ... - Nature
https://www.nature.com/articles/s41598-019-44257-5
webMay 28, 2019 · Huh-7.5, a subline of the human hepatoma cell line Huh-7, has been used widely to amplify HCV because HCV can efficiently replicate in these cells due to a defect in innate antiviral signalling.
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Huh-7 Cell Line - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/huh-7-cell-line
webThe Huh 7 cell line was derived from a 57-year-old man who had hepatocellular carcinoma. The cell line exhibits many hepatocellular functions, including production of albumin and α 1 -antitrypsin. The cells have homozygous HLA-A11 genotype [123] .
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HuH-7 reference genome profile: complex karyotype composed of ... - PubMed
https://pubmed.ncbi.nlm.nih.gov/29774518/
webWe provide empirical data that the HuH-7 cell line is composed of highly heterogeneous cell populations, suggesting that besides cell line authentication, the quality of cell lines needs to be taken into consideration in the future use of tumor cell lines. Keywords: Genome instability; Heterogeneity; Tumor cell line.
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Gene Expression Profiling of Different Huh7 Variants Reveals …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019296/
webDec 28, 2019 · To date, the human hepatoma cell line Huh7 and its derivatives is the only cell line that robustly replicates HCV. However, even different subclones and passages of this single cell line exhibit tremendous differences in HCV replication efficiency.
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HuH-7 reference genome profile: complex karyotype composed …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002425/
webMay 17, 2018 · We provide empirical data that the HuH-7 cell line is composed of highly heterogeneous cell populations, suggesting that besides cell line authentication, the quality of cell lines needs to be taken into consideration in the future use of tumor cell lines.
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