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Hemophagocytic Lymphohistiocystosis | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/hemophagocytic-lymphohistiocystosis
WEBHemophagocytic lymphohistiocytosis (HLH) is a rare disease that usually occurs in infants and young children. It may also occur in adults. Children usually inherit the disease. In adults, many different conditions, including infections and cancer, can cause HLH.
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Hemophagocytic Lymphohistiocytosis: Symptoms, Causes
https://my.clevelandclinic.org/health/diseases/24292-hemophagocytic-lymphohistiocytosis
WEBHemophagocytic lymphohistiocytosis is a rare and often life-threatening condition if left untreated. HLH causes your immune system to attack your body instead of a foreign invader like a virus. The condition is either acquired or genetic and there’s no way to prevent it. Treatment is available and most effective with an early diagnosis.
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Hemophagocytic lymphohistiocytosis - Wikipedia
https://en.m.wikipedia.org/wiki/Hemophagocytic_lymphohistiocytosis
WEBIn hematology, hemophagocytic lymphohistiocytosis (HLH), also known as haemophagocytic lymphohistiocytosis (British spelling), and hemophagocytic or haemophagocytic syndrome, is an uncommon hematologic disorder seen more often in children than in adults.
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Clinical features and diagnosis of hemophagocytic lymphohistiocytosis
https://www.uptodate.com/contents/clinical-features-and-diagnosis-of-hemophagocytic-lymphohistiocytosis
WEBMay 6, 2022 · Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life-threatening syndrome of excessive immune activation. It most frequently affects infants from birth to 18 months of age, but the disease is also observed in …
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Lymphohistiocytosis - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK557776/
WEBMar 27, 2023 · Hemophagocytic lymphohistiocytosis (HLH) is a devastating, hyper-inflammatory condition that results in multi-organ failure and death. The systemic inflammation that characterizes the disease is the result of inappropriate and dysregulated activation of natural killer (NK) cells, CD8+ cytotoxic T-cells, and macrophages.
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Hemophagocytic Lymphohistiocytosis (HLH) | Children's Hospital …
https://www.chop.edu/conditions-diseases/hemophagocytic-lymphohistiocytosis-hlh
WEBHemophagocytic lymphohistiocytosis (HLH) is rare life-threatening syndrome that can affect infants, children, adolescents and adults. HLH is not a single disease, however; it is a group of disorders of the immune system that can be triggered by infections, cancer or rheumatologic diseases.
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Hemophagocytic Lymphohistiocytosis - Symptoms, Causes, …
https://rarediseases.org/rare-diseases/hemophagocytic-lymphohistiocytosis/
WEBDec 13, 2018 · Disease Overview. Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condition caused by an overactive, abnormal response of the immune system. The immune system is the body’s natural defense system against foreign or invading organisms or substances.
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Hemophagocytic Lymphohistiocytosis (HLH) Causes, Treatment, …
https://www.verywellhealth.com/hlh-5120851
WEBMar 20, 2024 · Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome in which the immune system responds inappropriately to a triggering event, causing damage to healthy cells and organs in the body. It can affect infants, children, and adults.
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Hemophagocytic Lymphohistiocytosis (HLH) - The Merck Manuals
https://www.merckmanuals.com/professional/hematology-and-oncology/histiocytic-syndromes/hemophagocytic-lymphohistiocytosis-hlh
WEBHemophagocytic lymphohistiocytosis (HLH) is an uncommon disorder causing immune dysfunction in infants and young children. Many patients have an underlying immune disorder, although in some patients the underlying disorder is not known. Manifestations may include lymphadenopathy, hepatosplenomegaly, fever, …
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Current status of the diagnosis and treatment of hemophagocytic
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094004/
WEBApr 4, 2021 · Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of defective apoptosis, a disruption of the regulatory pathway that terminates immune and inflammatory responses. Fever, cytopenia, splenomegaly, and/or hemophagocytosis are typical findings of this syndrome. HLH can be induced by genetic disorders (familial) or secondary causes.
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