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RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co
https://www.nature.com/articles/s41467-022-30604-0
May 26, 2022 · RNase H1 and H2 are specialized enzymes ... HeLa and HEK293T cells were obtained from ATCC and grown in DMEM ... HeLa cell transfections were performed in 6-well plates 24 h after seeding with 22 ...
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ADAR1 RNA editing enzyme regulates R-loop formation and …
https://www.nature.com/articles/s41467-021-21921-x
Mar 12, 2021 · RNase H1 26 and H2 28 degrade RNA strands of RNA:DNA hybrids, while DHX9 29 and SETX 30 unwind RNA: ... HeLa human ovarian carcinoma (ATCC CCL-2), HEK293T human embryonic kidney (ATCC CRL-11268 ...
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Augmenting NK cell-based immunotherapy by targeting …
https://www.cell.com/cell/fulltext/S0092-8674(22)00340-3
Apr 20, 2022 · Next, HeLa WT or DKO cells were seeded, and NK cells were then added at a relatively low E:T ratio of 1:2. Of note, throughout the paper, particular caution was taken to ensure even distribution of both NK and target cells so that at E:T ≤ 1, a single cancer cell was, generally, not engaged simultaneously by two or more NK cells. ...
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Cistrome DB
http://cistrome.org/db/
Tips Check what factors regulate your gene of interest, what factors bind in your interval or have a significant binding overlap with your peak set.
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p3XFLAG-CMV-14 p3xFLAG CMV14载体质粒图谱、序列、价格 …
http://www.biofeng.com/zaiti/buru/p3XFLAG-CMV-14.html
p3XFLAG-CMV-14载体价格1500元，载体质粒图谱(Vector map),载体序列(Sequence)见下文，p3xFLAG CMV14载体抗性为氨苄，质粒大小为6310bp，测序引物为CMV-F。p3XFLAG-CMV-14载体是哺乳动物表达载体p3XFLAG-CMV-14。
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PD-L1-Mediated Gasdermin C Expression Switches Apoptosis to Pyroptosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653546/
Cleavage of gasdermin D (GSDMD) by caspase-1, −4, −5, or −11 defines the canonical pyroptosis pathway 1-4.Most gasdermin family members, except DFNB59, are conserved, maintain similar N-terminal domain structures which harbor pore-forming activity 5.Caspase-3 was reported to specifically cleave gasdermin E (GSDME), leading to chemotherapy drug-induced normal-tissue damage or viral ...
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已知一段DNA序列，怎样找到哪些转录因子会跟它结合？ - 企业动 …
https://www.biomart.cn/news/16/2837627.htm
普通细胞 原代细胞 ATCC ... 的promoter区都有CTCF和PolII的结合信号，另外，GM12878细胞里，有SP1的结合信号，胚胎干细胞H1里有NANOG的结合信号，白血病细胞系K562里有NFYA的结合信号，Hela-S3细胞系里有E2F1的结合信号等等，说明特定TF可能特异性的在这些细胞系里调控 ...
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High-intensity interval training remodels the proteome and …
https://elifesciences.org/articles/69802
May 31, 2022 · The mouse skeletal muscle cell line C2C12 (CRL1772, ATCC) was seeded into six-well plates at a density of 10 5 cells per well. Cells were cultured in growth medium (Dulbeccoo’s modified Eagle’s medium containing 25 mM glucose, supplemented with 10% fetal bovine serum (FBS) and 1%. Penicillin-streptomycin) at 37 °C and 5% CO 2
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Cellosaurus cell line A-549 (CVCL_0023) - Expasy
https://web.expasy.org/cellosaurus/CVCL_0023
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982). Part of: NCI-60 cancer cell line panel. ... (Abcam A-549 H1-2 KO ) CVCL_B9JD (Abcam A-549 H2BC21 KO ) CVCL_B1FG (Abcam A-549 HAPLN3 KO 1 ) ... Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J. Natl. Cancer Inst. 58:209-214(1977
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SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8566220/
Sep 06, 2021 · The B.1.617.2 (Delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread throughout India, outcompeting pre-existing lineages including B.1.617.1 (Kappa) and B.1.1.7 (Alpha) 1.In vitro, B.1.617.2 is sixfold less sensitive to serum neutralizing antibodies from recovered individuals, and eightfold less ...
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