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Causes of an elevated alkaline phosphatase - UpToDate
https://www.uptodate.com/contents/image?imageKey=GAST/99099
WEBAlkaline phosphatase may be derived from several sites including the liver, bone, third trimester placenta, intestine, and kidneys. An elevation in alkaline phosphatase with a normal gamma-glutamyl transpeptidase or 5'-nucleotidase suggests a nonhepatic source of alkaline phosphatase.
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Alkaline Phosphatase (ALP): What It Is, Causes & Treatment
https://my.clevelandclinic.org/health/diagnostics/22029-alkaline-phosphatase-alp
WEBWhat does it mean if my alkaline phosphatase (ALP) is high? It’s important to note that elevated levels of ALP can range in severity. While a very high ALP level often means you have liver damage or a bone disorder, mildly elevated levels can be caused by many different factors — not necessarily a medical condition that needs treatment.
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Alkaline Phosphatase Test (ALP): High vs. Low Levels - WebMD
https://www.webmd.com/digestive-disorders/alkaline_phosphatase_test
WEBMay 28, 2023 · Alkaline phosphatase (ALP) is one kind enzyme found in your body. If you show signs of liver disease or a bone disorder, your doctor may want you to get an ALP test to diagnose the problem.
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Approach To A Patient With Elevated Serum Alkaline Phosphatase
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341633/
WEBThis syndrome is characterized by an elevated serum alkaline phosphatase (AP) and gamma-glutamyltransferase (GGT) out of proportion to elevation of aminotransferase enzymes ( 1). Clinically, pruritus and fatigue are the most common presenting symptoms of chronic cholestatic disorders.
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Interpreting an isolated raised serum alkaline phosphatase ... - The BMJ
https://www.bmj.com/content/346/bmj.f976
WEBApr 3, 2013 · If alkaline phosphatase is raised in an asymptomatic patient and serum bilirubin, liver transaminases, creatinine, adjusted calcium, thyroid function, and blood count are normal: Consider growth spurts in adolescents, pregnancy in women, drugs, and age related increases.
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Alkaline Phosphatase - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK459201/
WEBAug 20, 2020 · One approach involves measuring the activity of enzymes, such as 5’-nucleotidase (5NT) and gamma-glutamyl transpeptidase (GGT), which increase in concordance with the liver ALP. These enzymes do not exhibit elevations in bone disorders and demonstrate a strong correlation with hepatobiliary disorders.
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Alkaline Phosphatase: MedlinePlus Medical Test
https://medlineplus.gov/lab-tests/alkaline-phosphatase/
WEBHigh alkaline phosphatase levels from your liver may be a sign of: Blockages in the bile ducts; Cirrhosis; Hepatitis; Mononucleosis, which can sometimes cause swelling in the liver; If alkaline phosphatase levels are high and the results of liver tests are normal, the problem may be a bone disorder, such as Paget's disease of bone. This disease ...
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Elevated alkaline phosphatase - Wikipedia
https://en.wikipedia.org/wiki/Elevated_alkaline_phosphatase
WEBElevated alkaline phosphatase occurs when levels of alkaline phosphatase (ALP) exceed the reference range. This group of enzymes has a low substrate specificity and catalyzes the hydrolysis of phosphate esters in a basic environment. The major function of alkaline phosphatase is transporting chemicals across cell membranes. [1]
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Alkaline phosphatase (ALP) level test: High and low levels
https://www.medicalnewstoday.com/articles/321984
WEBFeb 26, 2024 · Alkaline phosphatase (ALP) is an enzyme in blood that helps break down proteins. An ALP test measures how much ALP is circulating in the bloodstream. Having high or low ALP levels can...
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An Alkaline Phosphatase (ALP) Test: Levels and More - Healthline
https://www.healthline.com/health/alp
WEBNov 5, 2021 · Abnormal levels of ALP in your blood most often indicate a health concern with your liver, gallbladder, or bones. However, they may also indicate malnutrition, kidney cancer tumors, intestinal...
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