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Congo red - Wikipedia
https://en.m.wikipedia.org/wiki/Congo_red
WEBCongo red is an organic compound, the sodium salt of 3,3′- ( [1,1′-biphenyl]-4,4′-diyl)bis (4-aminonaphthalene-1-sulfonic acid). It is an azo dye. Congo red is water-soluble, yielding a red colloidal solution; its solubility is greater in organic solvents.
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Pathology Outlines - Congo red
https://www.pathologyoutlines.com/topic/stainscongored.html
WEBEssential features. Congo red stain is the gold standard for the demonstration of amyloid in tissue sections. Used to evaluate the presence and extent of amyloidosis in different organs. Common diseases for Congo red stain include primary amyloidosis, amyloid light chain (AL) seen in plasma cell dyscrasias, amyloid A (AA) associated with ...
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Congo Red and amyloids: history and relationship - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331669/
WEBJan 1, 2019 · Research in this area involves not only understanding how amyloidosis develops and how to prevent amyloid plaque formation but also investigating functional amyloids. Staining with Congo Red dye (CR) is one of the major methods used to detect the amyloid structure of protein aggregates.
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Congo red | Synthetic Dye, Azo Compound, Textile Dye | Britannica
https://www.britannica.com/technology/Congo-red
WEBCongo red, first of the synthetic dyestuffs of the direct type, that is, not requiring application of a mordant (a substance such as tannin or alum used to fix the colour to cotton fibres). Introduced in 1884, Congo red belongs to a group of azo dyes derived from benzidine.
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Congo red | C32H22N6Na2O6S2 | CID 11313 - PubChem
https://pubchem.ncbi.nlm.nih.gov/compound/Congo-red
WEBCongo Red is the sodium salt of benzidinediazo-bis-1-naphthylamine-4-sulfonic acid; a diazo dye that is red in alkaline solution and blue in acid solution and used especially as an indicator and as a biological stain. NCI Thesaurus (NCIt) An acid dye used in testing for hydrochloric acid in gastric contents.
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Congo Red - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/medicine-and-dentistry/congo-red
WEBCongo red demonstrates the accumulation of amyloid. With light microscopy it stains a pink or light red colour and shows green birefringence with polarized light. With rhodamine or Texas fluorescence the deposits show enhanced red fluorescence.
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Congo Red | Science | AAAS
https://www.science.org/content/blog-post/congo-red
WEBCongo Red. 26 Feb 2020. 2:58 PM ET. By Derek Lowe. 4 min read. Comments. Share: Many roots of organic chemistry, and of medicinal chemistry in particular, often originate in what might seem like an unlikely place: the dyestuff industry of the late 19th century.
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Congo Red - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/chemistry/congo-red
WEBCongo Red, the first direct dye, was discovered in 1883 by Paul Bottinger, who was working as a dye chemist for the Friedrich Bayer Company in Ebersfeld, Germany (Garg and Nigam, 1981; Linke, 2006 ). Bottinger left his employer, patented the compound under his own name and then sold the patent to AGFA in 1885.
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Congo Red Stain | SpringerLink
https://link.springer.com/referenceworkentry/10.1007/978-3-319-28845-1_5303-1
WEBJan 9, 2022 · Definition. Staining with Congo Red (CR) is a qualitative method used for the identification of amyloids in vitro and in tissue sections. Principle. The Congo red staining principle is based on the formation of hydrogen bridge bonds with the carbohydrate component of the substrate.
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Congo red - American Chemical Society
https://www.acs.org/molecule-of-the-week/archive/c/congo-red.html
WEBSep 8, 2014 · “Congo red” is not the name of a famous African explorer, but a dye that dates to 1883. It was synthesized by P. Böttiger as a textile dye, but it subsequently became more important as a pH indicator. It colors aqueous solutions blue below pH 3.0 and becomes red above pH 5.0.
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