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Chalcone - Wikipedia
https://en.wikipedia.org/wiki/Chalcone
WEBChalcone is the organic compound C 6 H 5 C(O)CH=CHC 6 H 5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively as chalcones or chalconoids. They are widely known bioactive substances, fluorescent materials, and chemical intermediates.
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Chalcone synthesis, properties and medicinal applications: a …
https://link.springer.com/article/10.1007/s10311-019-00959-w
WEBJan 6, 2020 · Abstract. Chalcone is an aromatic ketone that forms the central core of many important biological compounds, which are known as chalcones. Chalcones are the biogenetic precursors of flavonoids and isoflavonoids, which are abundant in plants. Chalcones are active lead molecules in medicinal chemistry for the discovery of new drugs.
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Chalcone | C15H12O | CID 637760 - PubChem
https://pubchem.ncbi.nlm.nih.gov/compound/Chalcone
WEBChalcone | C15H12O | CID 637760 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
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Chalcone: A Privileged Structure in Medicinal Chemistry
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131713/
WEBJun 6, 2017 · A chalcone is a simple chemical scaffold of many naturally occurring compounds and has a widespread distribution in vegetables, fruits, teas, and other plants. 1–5 The word “chalcone” is derived from the Greek word “chalcos”, meaning “bronze”, which results from the colors of most natural chalcones. 3 Chalcone compounds have a ...
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Chalcones: Synthetic Chemistry Follows Where Nature Leads
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392591/
WEBAug 13, 2021 · Keywords: chalcones, biomolecular interactions, synthesis, natural products, bioactivities, mechanisms, anticancer, antimicrobial, phenolics. Go to: 1. Introduction. Chalcones are flavonoid-type phenolic phytochemicals, often referred to as ‘open-chain flavonoids’, and biosynthesized via the shikimate pathway [ 1 ].
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Chalcone: A Privileged Structure in Medicinal Chemistry
https://pubs.acs.org/doi/10.1021/acs.chemrev.7b00020
WEBMay 10, 2017 · Abstract. Privileged structures have been widely used as an effective template in medicinal chemistry for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring compounds. Many chalcone derivatives have also been prepared due to their convenient synthesis.
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Chalcone Scaffolds, Bioprecursors of Flavonoids: Chemistry
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8659147/
WEBNov 26, 2021 · Abstract. Chalcones are secondary metabolites belonging to the flavonoid (C 6 -C 3 -C 6 system) family that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant flavonoids. Chalcones and their natural derivatives are important intermediates of the flavonoid biosynthetic pathway.
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Chalcone synthesis, properties and medicinal applications: a review
https://www.researchgate.net/publication/346520772_Chalcone_synthesis_properties_and_medicinal_applications_a_review
WEBJan 6, 2020 · Hanhan Dianhar. PDF | Chalcone is an aromatic ketone that forms the central core of many important biological compounds, which are known as chalcones. Chalcones are the... | Find, read and...
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Frontiers | Pharmacological Properties of Chalcones: A Review of
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2020.592654/full
WEBJan 18, 2021 · Multifaceted and complex underlying mechanisms of chalcone actions demonstrated their ability to modulate a number of cancer cell lines, to inhibit a number of pathological microorganisms and parasites, and to control a number of signaling molecules and cascades related to disease modification.
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Structure of chalcone synthase and the molecular basis of plant
https://www.nature.com/articles/nsb0899_775
WEBNature Communications (2022) Chalcone synthase (CHS) is pivotal for the biosynthesis of flavonoid antimicrobial phytoalexins and anthocyanin pigments in plants. It produces chalcone by condensing ...
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