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Perioperative management of patients receiving anticoagulants
https://www.uptodate.com/contents/perioperative-management-of-patients-receiving-anticoagulants
Typical durations of anticoagulant interruption are illustrated by the RE-LY trial, which randomized individuals with nonvalvular atrial fibrillation to warfarin or dabigatran for prevention of thromboembolism [9]. In this trial, nearly half of patients treated with dabigatran had surgery within 48 hours of stopping the drug, … See more
DA: 40 PA: 85 MOZ Rank: 88
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Perioperative Anticoagulation Management
https://www.ncbi.nlm.nih.gov/books/NBK557590/
WEBJan 23, 2023 · If the renal function was compromised (CrCl< 50 ml/min), these drugs were interrupted for four days before surgery. For low … Author: Javier J. Polania Gutierrez, Klifford R. Rocuts Published: 2023/01/23 Publish Year: 2021
Author: Javier J. Polania Gutierrez, Klifford R. Rocuts
Published: 2023/01/23
Publish Year: 2021
DA: 29 PA: 80 MOZ Rank: 57
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Perioperative Management of Direct Oral Anticoagulants …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156547/
WEBDec 13, 2016 · With repeated dosing, the half-life of apixaban is 12 hours. Apixaban is mostly metabolized by CYP3A4. It is a substrate of P-glycoprotein and breast cancer … Author: Tagore Sunkara, Emmanuel Ofori, Vadim Zarubin, Megan E. Caughey, Vinaya Gaduputi, Madhavi Reddy Publish Year: 2016
Author: Tagore Sunkara, Emmanuel Ofori, Vadim Zarubin, Megan E. Caughey, Vinaya Gaduputi, Madhavi Reddy
Publish Year: 2016
DA: 54 PA: 85 MOZ Rank: 47
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Apixaban - StatPearls - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK507910/
WEBApr 19, 2023 · Its elimination half-life is about 12 hours (8 to 15 hours). Before a patient undergoes elective surgery or an invasive procedure, … Published: 2023/04/19
Published: 2023/04/19
DA: 56 PA: 1 MOZ Rank: 45
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International consensus statement on the …
https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.14425
WEBSep 27, 2018 · Apixaban is rapidly absorbed, attaining peak plasma values around 1–3 h post-ingestion, followed by an elimination half-life of … Author: G. Erdoes, B. Martinez Lopez De Arroyabe, D. Bolliger, A. B. Ahmed, A. B. Ahmed, A. Koster, S. Agarw... Publish Year: 2018
Author: G. Erdoes, B. Martinez Lopez De Arroyabe, D. Bolliger, A. B. Ahmed, A. B. Ahmed, A. Koster, S. Agarw...
Publish Year: 2018
DA: 19 PA: 32 MOZ Rank: 18
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Perioperative Guidelines on Antiplatelet and Anticoagulant
https://link.springer.com/article/10.1007/s40140-021-00511-z
WEBJan 19, 2022 · Given the short elimination half-life of DOACs in most patients, a management approach stopping DOACs for 4 to 6 days before surgery might be …
DA: 35 PA: 64 MOZ Rank: 61
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Managing New Oral Anticoagulants in the …
https://pubs.asahq.org/anesthesiology/article/118/6/1466/11407/Managing-New-Oral-Anticoagulants-in-the
WEBThe peak plasma concentration is reached 1.25–3h after administration, and it has a half-life of 12–14h in healthy volunteers. 4 Dabigatran is 35% bound to plasma proteins and undergoes renal excretion, with 80% of …
DA: 100 PA: 92 MOZ Rank: 17