Keyword Analysis & Research: antimicrobial resistance mechanisms
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An overview of the antimicrobial resistance mechanisms of bacteria
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604941/
WEBJun 26, 2018 · Antimicrobial resistance mechanisms fall into four main categories: (1) limiting uptake of a drug; (2) modifying a drug target; (3) inactivating a drug; (4) active drug efflux. Intrinsic resistance may make use of limiting uptake, drug inactivation, and drug efflux; acquired resistance mechanisms used may be drug target modification, drug ...
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How Antibiotic Resistance Happens | CDC
https://www.cdc.gov/drugresistance/about/how-resistance-happens.html
WEBTo survive, germs can develop defense strategies against antibiotics and antifungals called resistance mechanisms. DNA tells the germ how to make specific proteins, which determine the germ’s resistance mechanisms. Bacteria and …
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Molecular mechanisms of antibiotic resistance revisited
https://www.nature.com/articles/s41579-022-00820-y
WEBNov 21, 2022 · Bacteria use various mechanisms of resistance 1, some are ‘intrinsic’, whereby the cell can use genes it already possesses to survive antibiotic exposure, and some...
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Mechanisms of Antibiotic Resistance - PMC - National Center for
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888801/
WEBIn general, mutations resulting in antimicrobial resistance alter the antibiotic action via one of the following mechanisms, i) modifications of the antimicrobial target (decreasing the affinity for the drug, see below), i) a decrease in the drug uptake, ii) activation of efflux mechanisms to extrude the harmful molecule, or iv) global changes ...
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Antibiotic resistance | Definition, Mechanisms, Examples, & Facts
https://www.britannica.com/science/antibiotic-resistance
WEB5 days ago · antibiotic resistance, loss of susceptibility of bacteria to the killing (bacteriocidal) or growth-inhibiting (bacteriostatic) properties of an antibiotic agent. When a resistant strain of bacteria is the dominant strain in an infection, the infection may be untreatable and life-threatening.
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Bacterial Resistance to Antimicrobial Agents - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157006/
WEBMay 17, 2021 · These antimicrobial resistance mechanisms include active antimicrobial efflux, reduced drug entry into cells of pathogens, enzymatic metabolism of antimicrobial agents to inactive products, biofilm formation, altered drug targets, and protection of antimicrobial targets.
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Antimicrobial resistance - World Health Organization (WHO)
https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
WEBAntimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death.
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An overview of the antimicrobial resistance mechanisms of bacteria
https://pubmed.ncbi.nlm.nih.gov/31294229/
WEBJun 26, 2018 · The main mechanisms of resistance are: limiting uptake of a drug, modification of a drug target, inactivation of a drug, and active efflux of a drug. These mechanisms may be native to the microorganisms, or acquired from other microorganisms.
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Molecular mechanisms of antibiotic resistance - Nature
https://www.nature.com/articles/nrmicro3380
WEBDec 1, 2014 · Molecular mechanisms of antibiotic resistance. Jessica M. A. Blair, Mark A. Webber, Alison J. Baylay, David O. Ogbolu & Laura J. V. Piddock. Nature Reviews Microbiology 13 , 42–51 (...
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Target protection as a key antibiotic resistance mechanism
https://www.nature.com/articles/s41579-020-0386-z
WEBJun 25, 2020 · Most such mechanisms serve either to reduce antibiotic concentration in the vicinity of the molecular target (through active efflux or chemical inactivation of the...
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