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Everything You Need To Know About A549 Cells - Synthego
https://www.synthego.com/a549-cells
WEBThe A549 cell lines are the most commonly used human non-small cell lung cancer cell lines for both basic research and drug discovery. In this article, we will cover every topic about this cell line, ranging from general information to research applications.
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A549 cell - Wikipedia
https://en.wikipedia.org/wiki/A549_cell
WEBA549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male.
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A549 - CCL-185 | ATCC
https://www.atcc.org/products/ccl-185
WEBCCL-185 ™. A549 cells were isolated from the lung tissue of a White, 58-year-old male with lung cancer. This cell line can be used in cancer, immuno-oncology, and toxicology research. Discounts may be available for our fellow nonprofit organizations.
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A549 Cell - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/neuroscience/a549-cell
WEBA549 Cell. The A549 cell line is a pulmonary epithelial cell line derived from a human alveolar cell carcinoma (Notter et al., 2005). From: Comparative Biology of the Normal Lung (Second Edition), 2015. Related terms: Nitric Oxide; Curcumin; Epithelial Cells; Cytotoxicity; In Vivo; In Vitro; Nuclear Factor Kappa B; Promoter Region; Cell Line
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Long Term Culture of the A549 Cancer Cell Line Promotes …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085087/
WEBOct 28, 2016 · One such commonly used cell model is the lung carcinoma cell line A549. Isolated in 1973 from a pulmonary adenocarcinoma [ 26] and subsequently characterized as being representative of ATII cells [ 3, 27 – 29 ], this cell line has been a mainstay of respiratory research for nearly four decades.
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Long-term culture of human lung adenocarcinoma A549 cells …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363306/
WEBAug 19, 2019 · The adenocarcinoma human alveolar basal epithelial cell line A549 has been used widely for in vitro studies of influenza A virus replication. However, this cell line has been shown to be less permissive for the productive infection of some influenza A …
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Immortalisation of primary human alveolar epithelial lung cells …
https://www.nature.com/articles/s41598-020-77191-y
WEBNov 24, 2020 · AT2 cells are cuboidal secretory cells which synthesise and release pulmonary surfactant, essential for the maintenance of alveolar epithelial homeostasis, maintaining reduced surface tension,...
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An autoantigen profile of human A549 lung cells reveals viral and …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075847/
WEBApr 27, 2021 · Based on the unique affinity between dermatan sulfate and autoantigens, we identified 348 proteins from human lung A549 cells, of which 198 are known targets of autoantibodies. Comparison with current COVID data identified 291 proteins that are altered at protein or transcript level in SARS-CoV-2 infection, with 191 being known autoantigens.
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Maximizing the relevance and reproducibility of A549 cell culture …
https://www.sciencedirect.com/science/article/pii/S0887233322001217
WEBSep 1, 2022 · A549 cells transitioned from FBS-supplemented media to commercial serum-free media. •. A gradual weaning process was successful under submerged and ALI conditions. •. Genotype, morphology, and functionality in different media formulations were assessed. •. Cells grown in X-VIVO™ 10 medium mimicked characteristics of FBS …
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SARS-CoV-2 treatment effects induced by ACE2-expressing
https://www.nature.com/articles/s41423-021-00813-6
WEBJan 4, 2022 · Here, we show that ACE2-overexpressing A549 cell-derived microparticles (AO-MPs) are a potential therapeutic agent against SARS-CoV-2 infection. Intranasally administered AO-MPs...
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